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Exploring the potential of approved drugs for triple-negative breast cancer treatment by targeting casein kinase 2: Insights from computational studies

Triple-negative breast cancer (TNBC) is an aggressive malignancy that requires effective targeted drug therapy. In this study, we employed in silico methods to evaluate the efficacy of seven approved drugs against human ck2 alpha kinase, a significant modulator of TNBC metastasis and invasiveness. M...

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Detalles Bibliográficos
Autores principales: Shoaib, Tagyedeen H., Ibraheem, Walaa, Abdelrahman, Mohammed, Osman, Wadah, Sherif, Asmaa E., Ashour, Ahmed, Ibrahim, Sabrin R. M., Ghazawi, Kholoud F., Miski, Samar F., Almadani, Sara A., ALsiyud, Duaa Fahad, Mohamed, Gamal A., Alzain, Abdulrahim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10424868/
https://www.ncbi.nlm.nih.gov/pubmed/37578958
http://dx.doi.org/10.1371/journal.pone.0289887