Decoupled neoantigen cross-presentation by dendritic cells limits anti-tumor immunity against tumors with heterogeneous neoantigen expression

Cancer immunotherapies, in particular checkpoint blockade immunotherapy (CBT), can induce control of cancer growth, with a fraction of patients experiencing durable responses. However, the majority of patients currently do not respond to CBT and the molecular determinants of resistance have not been...

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Detalles Bibliográficos
Autores principales: Nguyen, Kim Bich, Roerden, Malte, Copeland, Christopher J, Backlund, Coralie M, Klop-Packel, Nory G, Remba, Tanaka, Kim, Byungji, Singh, Nishant K, Birnbaum, Michael E, Irvine, Darrell J, Spranger, Stefani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425174/
https://www.ncbi.nlm.nih.gov/pubmed/37548358
http://dx.doi.org/10.7554/eLife.85263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425174/
https://www.ncbi.nlm.nih.gov/pubmed/37548358
http://dx.doi.org/10.7554/eLife.85263

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