Cargando…

A critical role for heme synthesis and succinate in the regulation of pluripotent states transitions

Using embryonic stem cells (ESCs) in regenerative medicine or in disease modeling requires a complete understanding of these cells. Two main distinct developmental states of ESCs have been stabilized in vitro, a naïve pre-implantation stage and a primed post-implantation stage. Based on two recently...

Descripción completa

Detalles Bibliográficos
Autores principales: Detraux, Damien, Caruso, Marino, Feller, Louise, Fransolet, Maude, Meurant, Sébastien, Mathieu, Julie, Arnould, Thierry, Renard, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425175/
https://www.ncbi.nlm.nih.gov/pubmed/37428012
http://dx.doi.org/10.7554/eLife.78546