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WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer

The tumor suppressor gene WWOX is localized in an unstable chromosomal region and its expression is decreased or absent in several types of cancer. A low expression of WWOX is associated with a poor prognosis in breast cancer (BC). It has recently been shown that WWOX contributes to genome stability...

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Detalles Bibliográficos
Autores principales: Taouis, Karim, Vacher, Sophie, Guirouilh-Barbat, Josée, Camonis, Jacques, Formstecher, Etienne, Popova, Tatiana, Hamy, Anne-Sophie, Petitalot, Ambre, Lidereau, Rosette, Caputo, Sandrine M., Zinn-Justin, Sophie, Bièche, Ivan, Driouch, Keltouma, Lallemand, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425285/
https://www.ncbi.nlm.nih.gov/pubmed/37248434
http://dx.doi.org/10.1038/s41417-023-00626-x