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In vitro characterisation of [(177)Lu]Lu-DOTA-C595 as a novel radioimmunotherapy for MUC1-CE positive pancreatic cancer

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) continues to be a malignancy with an unmet clinical demand. Development of radioimmunoconjugates which target cancer-specific receptors provides an opportunity for radioimmunotherapy of both metastatic and primary PDAC. In this study, we characteri...

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Detalles Bibliográficos
Autores principales: Hull, Ashleigh, Hsieh, William, Tieu, William, Bartholomeusz, Dylan, Li, Yanrui, Bezak, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425306/
https://www.ncbi.nlm.nih.gov/pubmed/37578571
http://dx.doi.org/10.1186/s41181-023-00204-4