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GATA2 mitotic bookmarking is required for definitive haematopoiesis

In mitosis, most transcription factors detach from chromatin, but some are retained and bookmark genomic sites. Mitotic bookmarking has been implicated in lineage inheritance, pluripotency and reprogramming. However, the biological significance of this mechanism in vivo remains unclear. Here, we add...

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Detalles Bibliográficos
Autores principales: Silvério-Alves, Rita, Kurochkin, Ilia, Rydström, Anna, Vazquez Echegaray, Camila, Haider, Jakob, Nicholls, Matthew, Rode, Christina, Thelaus, Louise, Lindgren, Aida Yifter, Ferreira, Alexandra Gabriela, Brandão, Rafael, Larsson, Jonas, de Bruijn, Marella F. T. R., Martin-Gonzalez, Javier, Pereira, Carlos-Filipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425459/
https://www.ncbi.nlm.nih.gov/pubmed/37580379
http://dx.doi.org/10.1038/s41467-023-40391-x