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GATA2 mitotic bookmarking is required for definitive haematopoiesis
In mitosis, most transcription factors detach from chromatin, but some are retained and bookmark genomic sites. Mitotic bookmarking has been implicated in lineage inheritance, pluripotency and reprogramming. However, the biological significance of this mechanism in vivo remains unclear. Here, we add...
Autores principales: | Silvério-Alves, Rita, Kurochkin, Ilia, Rydström, Anna, Vazquez Echegaray, Camila, Haider, Jakob, Nicholls, Matthew, Rode, Christina, Thelaus, Louise, Lindgren, Aida Yifter, Ferreira, Alexandra Gabriela, Brandão, Rafael, Larsson, Jonas, de Bruijn, Marella F. T. R., Martin-Gonzalez, Javier, Pereira, Carlos-Filipe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425459/ https://www.ncbi.nlm.nih.gov/pubmed/37580379 http://dx.doi.org/10.1038/s41467-023-40391-x |
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