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Inhibition of CysLTR1 reduces the levels of aggregated proteins in retinal pigment epithelial cells

The endosomal-lysosomal system (ELS), which carries out cellular processes such as cellular waste degradation via autophagy, is essential for cell homeostasis. ELS inefficiency leads to augmented levels of damaged organelles and intracellular deposits. Consequently, the modulation of autophagic flux...

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Detalles Bibliográficos
Autores principales: Koller, Andreas, Brunner, Susanne Maria, Preishuber-Pflügl, Julia, Mayr, Daniela, Ladek, Anja-Maria, Runge, Christian, Reitsamer, Herbert Anton, Trost, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425468/
https://www.ncbi.nlm.nih.gov/pubmed/37580467
http://dx.doi.org/10.1038/s41598-023-40248-9