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Inhibition of CysLTR1 reduces the levels of aggregated proteins in retinal pigment epithelial cells
The endosomal-lysosomal system (ELS), which carries out cellular processes such as cellular waste degradation via autophagy, is essential for cell homeostasis. ELS inefficiency leads to augmented levels of damaged organelles and intracellular deposits. Consequently, the modulation of autophagic flux...
Autores principales: | Koller, Andreas, Brunner, Susanne Maria, Preishuber-Pflügl, Julia, Mayr, Daniela, Ladek, Anja-Maria, Runge, Christian, Reitsamer, Herbert Anton, Trost, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425468/ https://www.ncbi.nlm.nih.gov/pubmed/37580467 http://dx.doi.org/10.1038/s41598-023-40248-9 |
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