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Fbxo22 inhibits metastasis in triple-negative breast cancer through ubiquitin modification of KDM5A and regulation of H3K4me3 demethylation

The importance of Fbxo22 in carcinogenesis has been highly documented. Here, we discussed downstream regulatory factors of Fbxo22 in TNBC. RNA-sequencing was conducted for identifying differentially expressed genes, followed by construction of a regulatory network. Expression patterns of Fbxo22/KDM5...

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Detalles Bibliográficos
Autores principales: Li, Siqiaozhi, He, Jinsong, Liao, Xin, He, Yixuan, Chen, Rui, Chen, Junhui, Hu, Sean, Sun, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425479/
https://www.ncbi.nlm.nih.gov/pubmed/36112263
http://dx.doi.org/10.1007/s10565-022-09754-w