Safety and efficacy of artesunate treatment in severely injured patients with traumatic hemorrhage. The TOP-ART randomized clinical trial

PURPOSE: This study aimed at determining whether intravenous artesunate is safe and effective in reducing multiple organ dysfunction syndrome in trauma patients with major hemorrhage. METHODS: TOP-ART, a randomized, blinded, placebo-controlled, phase IIa trial, was conducted at a London major trauma...

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Detalles Bibliográficos
Autores principales: Shepherd, Joanna M., Ross, Jennifer, Anton, Lourdes, Rourke, Claire, Brentnall, Adam R., Tarning, Joel, White, Nicholas J., Thiemermann, Christoph, Brohi, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425486/
https://www.ncbi.nlm.nih.gov/pubmed/37470832
http://dx.doi.org/10.1007/s00134-023-07135-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425486/
https://www.ncbi.nlm.nih.gov/pubmed/37470832
http://dx.doi.org/10.1007/s00134-023-07135-3

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