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Capturing time-dependent activation of genes and stress-response pathways using transcriptomics in iPSC-derived renal proximal tubule cells

Transcriptomic analysis is a powerful method in the utilization of New Approach Methods (NAMs) for identifying mechanisms of toxicity and application to hazard characterization. With this regard, mapping toxicological events to time of exposure would be helpful to characterize early events. Here, we...

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Detalles Bibliográficos
Autores principales: Jennings, Paul, Carta, Giada, Singh, Pranika, da Costa Pereira, Daniel, Feher, Anita, Dinnyes, Andras, Exner, Thomas E., Wilmes, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425493/
https://www.ncbi.nlm.nih.gov/pubmed/36586010
http://dx.doi.org/10.1007/s10565-022-09783-5