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CCL24/CCR3 axis plays a central role in angiotensin II–induced heart failure by stimulating M2 macrophage polarization and fibroblast activation

AIMS: We aimed to investigate the effect and mechanism of pleiotropic chemokine CCL24 in heart failure. METHODS AND RESULTS: Compared with normal donators, the expression of CCL24 and number of cardiac M2 macrophages in heart were higher in heart failure patients, the same as plasma CCL24. Treatment...

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Detalles Bibliográficos
Autores principales: Wang, Zhen, Xu, Hongfei, Chen, Miao, Lu, Yunlong, Zheng, Liangrong, Ma, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425496/
https://www.ncbi.nlm.nih.gov/pubmed/36131165
http://dx.doi.org/10.1007/s10565-022-09767-5