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Crosstalk between glucocorticoid and mineralocorticoid receptors boosts glucocorticoid-induced killing of multiple myeloma cells

The glucocorticoid receptor (GR) is a crucial drug target in multiple myeloma as its activation with glucocorticoids effectively triggers myeloma cell death. However, as high-dose glucocorticoids are also associated with deleterious side effects, novel approaches are urgently needed to improve GR ac...

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Detalles Bibliográficos
Autores principales: Clarisse, Dorien, Prekovic, Stefan, Vlummens, Philip, Staessens, Eleni, Van Wesemael, Karlien, Thommis, Jonathan, Fijalkowska, Daria, Acke, Guillaume, Zwart, Wilbert, Beck, Ilse M., Offner, Fritz, De Bosscher, Karolien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425521/
https://www.ncbi.nlm.nih.gov/pubmed/37578563
http://dx.doi.org/10.1007/s00018-023-04900-x