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Plk2-mediated phosphorylation and translocalization of Nrf2 activates anti-inflammation through p53/Plk2/p21(cip1) signaling in acute kidney injury

The Plk2 is a cellular stress-responsive factor that is induced in response to oxidative stress. However, the roles of Plk2 in acute kidney injury (AKI) have not been clarified. We previously found that Plk2 is an interacting factor of Nrf2 in response to cellular stress, since Plk2 is upregulated i...

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Detalles Bibliográficos
Autores principales: Kim, Da-Eun, Byeon, Hye Eun, Kim, Dae-Hoon, Kim, Sang Geon, Yim, Hyungshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425522/
https://www.ncbi.nlm.nih.gov/pubmed/35842499
http://dx.doi.org/10.1007/s10565-022-09741-1