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A Randomized, Double‐Blind, Placebo‐Controlled Multicenter Efficacy and Safety Study of Methotrexate to Increase Response Rates in Patients With Uncontrolled Gout Receiving Pegloticase: 12‐Month Findings

OBJECTIVE: To assess 12‐month safety and efficacy of pegloticase + methotrexate (MTX) versus pegloticase + placebo (PBO) cotherapy in a PBO‐controlled, double‐blind trial (A randomized, double‐blind, placebo‐controlled, multicenter, efficacy and safety study of methotrexate to increase response rate...

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Detalles Bibliográficos
Autores principales: Botson, John K., Saag, Kenneth, Peterson, Jeff, Obermeyer, Katie, Xin, Yan, LaMoreaux, Brian, Padnick‐Silver, Lissa, Verma, Supra, Grewal, Suneet, Majjhoo, Amar, Tesser, John R. P., Weinblatt, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425585/
https://www.ncbi.nlm.nih.gov/pubmed/37385296
http://dx.doi.org/10.1002/acr2.11578