A novel IBA57 variant is associated with mitochondrial iron–sulfur protein deficiency and necrotizing myelopathy in dogs

Introduction: Hereditary necrotizing myelopathy (HNM) in young Kooiker dogs is characterized by progressive ataxia and paralysis with autosomal recessive inheritance. The basic genetic defect is unknown. We investigated the possible cause by a genome-wide analysis using six affected and 17 unrelated...

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Detalles Bibliográficos
Autores principales: Mandigers, Paul J. J., Stehling, Oliver, Vos-Loohuis, Manon, Van Steenbeek, Frank G., Lill, Roland, Leegwater, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425596/
https://www.ncbi.nlm.nih.gov/pubmed/37588046
http://dx.doi.org/10.3389/fgene.2023.1190222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425596/
https://www.ncbi.nlm.nih.gov/pubmed/37588046
http://dx.doi.org/10.3389/fgene.2023.1190222

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