Cathepsin B-activatable cyclic antisense oligonucleotides for cell-specific target gene knockdown in vitro and in vivo

Trigger-activatable antisense oligonucleotides have been widely applied to regulate gene function. Among them, caged cyclic antisense oligonucleotides (cASOs) maintain a specific topology that temporarily inhibits their interaction with target genes. By inserting linkers that respond to cell-specifi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zhongyu, Fan, Xinli, Mu, Guanqun, Zhao, Xiaoran, Wang, Qian, Wang, Jing, Tang, Xinjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425675/
https://www.ncbi.nlm.nih.gov/pubmed/37588686
http://dx.doi.org/10.1016/j.omtn.2023.07.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425675/
https://www.ncbi.nlm.nih.gov/pubmed/37588686
http://dx.doi.org/10.1016/j.omtn.2023.07.022

Ejemplares similares