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Modelling host- Trypanosoma brucei gambiense interactions in vitro using human induced pluripotent stem cell-derived cortical brain organoids
Background: Sleeping sickness is caused by the extracellular parasite Trypanosoma brucei and is associated with neuroinflammation and neuropsychiatric disorders, including disruption of sleep/wake patterns, and is now recognised as a circadian disorder. Sleeping sickness is traditionally studied usi...
Autores principales: | Chandrasegaran, Praveena, Nabilla Lestari, Agatha, Sinton, Matthew C., Gopalakrishnan, Jay, Quintana, Juan F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425695/ https://www.ncbi.nlm.nih.gov/pubmed/37588058 http://dx.doi.org/10.12688/f1000research.131507.2 |
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