Oncometabolite lactate enhances breast cancer progression by orchestrating histone lactylation-dependent c-Myc expression

Due to the enhanced glycolytic rate, cancer cells generate lactate copiously, subsequently promoting the lactylation of histones. While previous studies have explored the impact of histone lactylation in modulating gene expression, the precise role of this epigenetic modification in regulating oncog...

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Detalles Bibliográficos
Autores principales: Pandkar, Madhura R., Sinha, Sommya, Samaiya, Atul, Shukla, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425713/
https://www.ncbi.nlm.nih.gov/pubmed/37572497
http://dx.doi.org/10.1016/j.tranon.2023.101758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425713/
https://www.ncbi.nlm.nih.gov/pubmed/37572497
http://dx.doi.org/10.1016/j.tranon.2023.101758

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