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Oncometabolite lactate enhances breast cancer progression by orchestrating histone lactylation-dependent c-Myc expression
Due to the enhanced glycolytic rate, cancer cells generate lactate copiously, subsequently promoting the lactylation of histones. While previous studies have explored the impact of histone lactylation in modulating gene expression, the precise role of this epigenetic modification in regulating oncog...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Neoplasia Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425713/ https://www.ncbi.nlm.nih.gov/pubmed/37572497 http://dx.doi.org/10.1016/j.tranon.2023.101758 |