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Elevated Mast Cell Abundance Is Associated with Enrichment of CCR2(+) Cytotoxic T Cells and Favorable Prognosis in Lung Adenocarcinoma

Mast cells constitute indispensable immunoregulatory sentinel cells in the tumor microenvironment. A better understanding of the regulation and functions of mast cells in lung adenocarcinoma (LUAD) could uncover therapeutic approaches to reprogram the immunosuppressive tumor microenvironment. Here,...

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Detalles Bibliográficos
Autores principales: Fan, Fanfan, Gao, Jian, Zhao, Yue, Wang, Jun, Meng, Lu, Ma, Jiaqiang, Li, Teng, Han, Han, Lai, Jinglei, Gao, Zhendong, Li, Xiongfei, Guo, Ran, Cao, Zhiwei, Zhang, Yang, Zhang, Xiaoming, Chen, Haiquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425735/
https://www.ncbi.nlm.nih.gov/pubmed/37249584
http://dx.doi.org/10.1158/0008-5472.CAN-22-3140