Intermetastatic and Intrametastatic Heterogeneity Shapes Adaptive Therapy Cycling Dynamics

Adaptive therapies that alternate between drug applications and drug-free vacations can exploit competition between sensitive and resistant cells to maximize the time to progression. However, optimal dosing schedules depend on the properties of metastases, which are often not directly measurable in...

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Detalles Bibliográficos
Autores principales: Gallaher, Jill, Strobl, Maximilian, West, Jeffrey, Gatenby, Robert, Zhang, Jingsong, Robertson-Tessi, Mark, Anderson, Alexander R.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Computational Cancer Biology and Technology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425736/
https://www.ncbi.nlm.nih.gov/pubmed/37205789
http://dx.doi.org/10.1158/0008-5472.CAN-22-2558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425736/
https://www.ncbi.nlm.nih.gov/pubmed/37205789
http://dx.doi.org/10.1158/0008-5472.CAN-22-2558

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