High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer

For one-third of patients with pediatric cancer enrolled in precision medicine programs, molecular profiling does not result in a therapeutic recommendation. To identify potential strategies for treating these high-risk pediatric patients, we performed in vitro screening of 125 patient-derived sampl...

Descripción completa

Detalles Bibliográficos
Autores principales: Mayoh, Chelsea, Mao, Jie, Xie, Jinhan, Tax, Gabor, Chow, Shu-Oi, Cadiz, Roxanne, Pazaky, Karina, Barahona, Paulette, Ajuyah, Pamela, Trebilcock, Peter, Malquori, Angela, Gunther, Kate, Avila, Anica, Yun, Doo Young, Alfred, Stephanie, Gopalakrishnan, Anjana, Kamili, Alvin, Wong, Marie, Cowley, Mark J., Jessop, Sophie, Lau, Loretta M.S., Trahair, Toby N., Ziegler, David S., Fletcher, Jamie I., Gifford, Andrew J., Tsoli, Maria, Marshall, Glenn M., Haber, Michelle, Tyrrell, Vanessa, Failes, Timothy W., Arndt, Greg M., Lock, Richard B., Ekert, Paul G., Dolman, M. Emmy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Translational Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425737/
https://www.ncbi.nlm.nih.gov/pubmed/37523146
http://dx.doi.org/10.1158/0008-5472.CAN-22-3702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425737/
https://www.ncbi.nlm.nih.gov/pubmed/37523146
http://dx.doi.org/10.1158/0008-5472.CAN-22-3702

Ejemplares similares