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Targeting CD47-SIRPα axis for Hodgkin and non-Hodgkin lymphoma immunotherapy
The interaction between cluster of differentiation 47 (CD47) and signal regulatory protein α (SIRPα) protects healthy cells from macrophage attack, which is crucial for maintaining immune homeostasis. Overexpression of CD47 occurs widely across various tumor cell types and transmits the “don't...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Chongqing Medical University
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425755/ https://www.ncbi.nlm.nih.gov/pubmed/37588232 http://dx.doi.org/10.1016/j.gendis.2022.12.008 |