Ribonucleotide reductase M2 (RRM2): Regulation, function and targeting strategy in human cancer

Ribonucleotide reductase M2 (RRM2) is a small subunit in ribonucleotide reductases, which participate in nucleotide metabolism and catalyze the conversion of nucleotides to deoxynucleotides, maintaining the dNTP pools for DNA biosynthesis, repair, and replication. RRM2 performs a critical role in th...

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Detalles Bibliográficos
Autores principales: Zuo, Zanwen, Zhou, Zerong, Chang, Yuzhou, Liu, Yan, Shen, Yuping, Li, Qizhang, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425756/
https://www.ncbi.nlm.nih.gov/pubmed/37588202
http://dx.doi.org/10.1016/j.gendis.2022.11.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425756/
https://www.ncbi.nlm.nih.gov/pubmed/37588202
http://dx.doi.org/10.1016/j.gendis.2022.11.022

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