Cargando…

A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axis

Glioblastoma (GBM) is a malignant brain tumor that grows quickly, spreads widely, and is resistant to treatment. Fibroblast growth factor receptor (FGFR)1 is a receptor tyrosine kinase that regulates cellular processes, including proliferation, survival, migration, and differentiation. FGFR1 was pre...

Descripción completa

Detalles Bibliográficos
Autores principales: Bi, Yanran, Zheng, Ruiling, Hu, Jiahao, Shi, Ruiqing, Shi, Junfeng, Wang, Yutao, Wang, Peng, Jiang, Wenyi, Kim, Gyudong, Liu, Zhiguo, Li, Xiaokun, Lin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425802/
https://www.ncbi.nlm.nih.gov/pubmed/37588207
http://dx.doi.org/10.1016/j.gendis.2023.02.035