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A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axis
Glioblastoma (GBM) is a malignant brain tumor that grows quickly, spreads widely, and is resistant to treatment. Fibroblast growth factor receptor (FGFR)1 is a receptor tyrosine kinase that regulates cellular processes, including proliferation, survival, migration, and differentiation. FGFR1 was pre...
Autores principales: | Bi, Yanran, Zheng, Ruiling, Hu, Jiahao, Shi, Ruiqing, Shi, Junfeng, Wang, Yutao, Wang, Peng, Jiang, Wenyi, Kim, Gyudong, Liu, Zhiguo, Li, Xiaokun, Lin, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425802/ https://www.ncbi.nlm.nih.gov/pubmed/37588207 http://dx.doi.org/10.1016/j.gendis.2023.02.035 |
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