HIF-1α signaling: Essential roles in tumorigenesis and implications in targeted therapies

The hypoxic microenvironment is an essential characteristic of most malignant tumors. Notably, hypoxia-inducible factor-1 alpha (HIF-1α) is a key regulatory factor of cellular adaptation to hypoxia, and many critical pathways are correlated with the biological activity of organisms via HIF-1α. In th...

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Detalles Bibliográficos
Autores principales: Zhao, Yan, Xing, Cheng, Deng, Yating, Ye, Can, Peng, Hongling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425810/
https://www.ncbi.nlm.nih.gov/pubmed/37588219
http://dx.doi.org/10.1016/j.gendis.2023.02.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425810/
https://www.ncbi.nlm.nih.gov/pubmed/37588219
http://dx.doi.org/10.1016/j.gendis.2023.02.039

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