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Canonical and noncanonical Wnt signaling: Multilayered mediators, signaling mechanisms and major signaling crosstalk

Wnt signaling plays a major role in regulating cell proliferation and differentiation. The Wnt ligands are a family of 19 secreted glycoproteins that mediate their signaling effects via binding to Frizzled receptors and LRP5/6 coreceptors and transducing the signal either through β-catenin in the ca...

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Detalles Bibliográficos
Autores principales: Qin, Kevin, Yu, Michael, Fan, Jiaming, Wang, Hongwei, Zhao, Piao, Zhao, Guozhi, Zeng, Wei, Chen, Connie, Wang, Yonghui, Wang, Annie, Schwartz, Zander, Hong, Jeffrey, Song, Lily, Wagstaff, William, Haydon, Rex C., Luu, Hue H., Ho, Sherwin H., Strelzow, Jason, Reid, Russell R., He, Tong-Chuan, Shi, Lewis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425814/
https://www.ncbi.nlm.nih.gov/pubmed/37588235
http://dx.doi.org/10.1016/j.gendis.2023.01.030