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Canonical and noncanonical Wnt signaling: Multilayered mediators, signaling mechanisms and major signaling crosstalk
Wnt signaling plays a major role in regulating cell proliferation and differentiation. The Wnt ligands are a family of 19 secreted glycoproteins that mediate their signaling effects via binding to Frizzled receptors and LRP5/6 coreceptors and transducing the signal either through β-catenin in the ca...
Autores principales: | Qin, Kevin, Yu, Michael, Fan, Jiaming, Wang, Hongwei, Zhao, Piao, Zhao, Guozhi, Zeng, Wei, Chen, Connie, Wang, Yonghui, Wang, Annie, Schwartz, Zander, Hong, Jeffrey, Song, Lily, Wagstaff, William, Haydon, Rex C., Luu, Hue H., Ho, Sherwin H., Strelzow, Jason, Reid, Russell R., He, Tong-Chuan, Shi, Lewis L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425814/ https://www.ncbi.nlm.nih.gov/pubmed/37588235 http://dx.doi.org/10.1016/j.gendis.2023.01.030 |
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