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High drug loading hydrophobic cross-linked dextran microspheres as novel drug delivery systems for the treatment of osteoarthritis

Drug delivery via intra-articular (IA) injection has proved to be effective in osteoarthritis (OA) therapy, limited by the drug efficiency and short retention time of the drug delivery systems (DDSs). Herein, a series of modified cross-linked dextran (Sephadex, S0) was fabricated by respectively gra...

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Detalles Bibliográficos
Autores principales: Li, Zhimin, Feng, Xianjing, Luo, Shixing, Ding, Yanfeng, Zhang, Zhi, Shang, Yifeng, Lei, Doudou, Cai, Jinhong, Zhao, Jinmin, Zheng, Li, Gao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10425896/
https://www.ncbi.nlm.nih.gov/pubmed/37588991
http://dx.doi.org/10.1016/j.ajps.2023.100830