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Fibroblast-to-cardiomyocyte lactate shuttle modulates hypertensive cardiac remodelling

BACKGROUND: Cardiac fibroblasts (CFs) and cardiomyocytes are the major cell populations in the heart. CFs not only support cardiomyocytes by producing extracellular matrix (ECM) but also assimilate myocardial nutrient metabolism. Recent studies suggest that the classical intercellular lactate shuttl...

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Detalles Bibliográficos
Autores principales: Wei, Tong, Guo, Yuetong, Huang, Chenglin, Sun, Mengwei, Zhou, Bin, Gao, Jing, Shen, Weili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426103/
https://www.ncbi.nlm.nih.gov/pubmed/37580825
http://dx.doi.org/10.1186/s13578-023-01098-0