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Fibroblast-to-cardiomyocyte lactate shuttle modulates hypertensive cardiac remodelling
BACKGROUND: Cardiac fibroblasts (CFs) and cardiomyocytes are the major cell populations in the heart. CFs not only support cardiomyocytes by producing extracellular matrix (ECM) but also assimilate myocardial nutrient metabolism. Recent studies suggest that the classical intercellular lactate shuttl...
Autores principales: | Wei, Tong, Guo, Yuetong, Huang, Chenglin, Sun, Mengwei, Zhou, Bin, Gao, Jing, Shen, Weili |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426103/ https://www.ncbi.nlm.nih.gov/pubmed/37580825 http://dx.doi.org/10.1186/s13578-023-01098-0 |
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