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FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells

BACKGROUND: The maintenance of genome stability in primordial germ cells (PGCs) is crucial for the faithful transmission of genetic information and the establishment of reproductive reserve. Numerous studies in recent decades have linked the Fanconi anemia (FA) pathway with fertility, particularly P...

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Detalles Bibliográficos
Autores principales: Xu, Weiwei, Yang, Yajuan, Yu, Yongze, Wen, Canxin, Zhao, Simin, Cao, Lili, Zhao, Shidou, Qin, Yingying, Chen, Zi-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426154/
https://www.ncbi.nlm.nih.gov/pubmed/37580696
http://dx.doi.org/10.1186/s12915-023-01676-1