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Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by Aβ deposition, tauopathy, neuroinflammation, and impaired cognition. The recent identification of associations between protein kinases and AD pathology has spurred interest in tyrosine kinase inhibitors (TKIs) as potential stra...

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Detalles Bibliográficos
Autores principales: Lee, Hyun-ju, Hwang, Jeong-Woo, Park, Jin-Hee, Jeong, Yoo Joo, Jang, Ji-Yeong, Hoe, Hyang-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426186/
https://www.ncbi.nlm.nih.gov/pubmed/37580778
http://dx.doi.org/10.1186/s13041-023-01051-9