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Dissection of transcriptomic and epigenetic heterogeneity of grade 4 gliomas: implications for prognosis

BACKGROUND: Grade 4 glioma is the most aggressive and currently incurable brain tumor with a median survival of one year in adult patients. Elucidating novel transcriptomic and epigenetic contributors to the molecular heterogeneity underlying its aggressiveness may lead to improved clinical outcomes...

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Detalles Bibliográficos
Autores principales: Zeng, Chang, Song, Xiao, Zhang, Zhou, Cai, Qinyun, Cai, Jiajun, Horbinski, Craig, Hu, Bo, Cheng, Shi-Yuan, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426201/
https://www.ncbi.nlm.nih.gov/pubmed/37580817
http://dx.doi.org/10.1186/s40478-023-01619-5