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PECAM-1 drives β-catenin-mediated EndMT via internalization in colon cancer with diabetes mellitus

BACKGROUND: Diabetes mellitus (DM) is considered to be a risk factor in carcinogenesis and progression, although the biological mechanisms are not well understood. Here we demonstrate that platelet-endothelial cell adhesion molecule 1 (PECAM-1) internalization drives β-catenin-mediated endothelial-m...

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Detalles Bibliográficos
Autores principales: Wu, Qing, Du, Xingxing, Cheng, Jianing, Qi, Xiuying, Liu, Huan, Lv, Xiaohong, Gong, Xieyang, Shao, Changxin, Wang, Muhong, Yue, Luxiao, Yang, Xin, Li, Shiyu, Zhang, Yafang, Li, Xuemei, Yang, Huike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426208/
https://www.ncbi.nlm.nih.gov/pubmed/37580771
http://dx.doi.org/10.1186/s12964-023-01193-2