Tanshinone IIA alleviates chondrocyte apoptosis and extracellular matrix degeneration by inhibiting ferroptosis

Articular cartilage degeneration caused by chondrocyte damage is the primary pathological mechanism of osteoarthritis (OA). Oxidative stress is correlated with chondrocyte injury by potentiating ferroptosis, a newly identified form of cell death. Given the effects of Tanshinone IIA (Tan IIA) on alle...

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Detalles Bibliográficos
Autores principales: Xu, Jin, Zhi, Xiaocheng, Zhang, Yunhui, Ding, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426267/
https://www.ncbi.nlm.nih.gov/pubmed/37589005
http://dx.doi.org/10.1515/biol-2022-0666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426267/
https://www.ncbi.nlm.nih.gov/pubmed/37589005
http://dx.doi.org/10.1515/biol-2022-0666

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