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Placental deficiency of the (pro)renin receptor ((P)RR) reduces placental development and functional capacity

The (pro)renin receptor ((P)RR; also known as ATP6AP2) is a multifunctional receptor. The (P)RR activates the tissue renin-angiotensin system (RAS) and is also involved in regulating integral intracellular pathways such as V-ATPase and Wnt/β-catenin signalling. Given this, the (P)RR may be associate...

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Detalles Bibliográficos
Autores principales: Schofield, Lachlan G., Kahl, Richard G. S., Rodrigues, Samantha L., Fisher, Joshua J., Endacott, Saije K., Delforce, Sarah J., Lumbers, Eugenie R., Martin, Jacinta H., Pringle, Kirsty G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427116/
https://www.ncbi.nlm.nih.gov/pubmed/37588662
http://dx.doi.org/10.3389/fcell.2023.1212898