Chelidonine reduces IL-1β-induced inflammation and matrix catabolism in chondrocytes and attenuates cartilage degeneration and synovial inflammation in rats

Chondrocyte inflammation and catabolism are two major features in the progression of osteoarthritis (OA). Chelidonine, a principal alkaloid extracted from Chelidonium majus, is suggested to show anti-inflammation, anti-apoptosis, and anti-oxidation activities in various diseases. However, its potent...

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Detalles Bibliográficos
Autores principales: Li, Mao, Zhu, Ying, Shao, Jiajia, Wang, Chuanbing, Dong, Bin, Cui, Haiyong, Dai, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427162/
https://www.ncbi.nlm.nih.gov/pubmed/37585914
http://dx.doi.org/10.1590/1414-431X2023e12604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427162/
https://www.ncbi.nlm.nih.gov/pubmed/37585914
http://dx.doi.org/10.1590/1414-431X2023e12604

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