Cargando…

MSL1 Promotes Liver Regeneration by Driving Phase Separation of STAT3 and Histone H4 and Enhancing Their Acetylation

Male‐specific lethal 1 (MSL1) is critical for the formation of MSL histone acetyltransferase complex which acetylates histone H4 Lys16 (H4K16ac) to activate gene expression. However, the role of MSL1 in liver regeneration is poorly understood. Here, this work identifies MSL1 as a key regulator of ST...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Yucheng, Wang, Shichao, Liu, Shenghui, Qin, Dan, Liu, Zhangmei, Wang, Liqiang, Chen, Xiangmei, Zhang, Lisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427353/
https://www.ncbi.nlm.nih.gov/pubmed/37279389
http://dx.doi.org/10.1002/advs.202301094