Transforming Growth Factor Beta Promotes Inflammation and Tumorigenesis in Smad4‐Deficient Intestinal Epithelium in a YAP‐Dependent Manner

Transforming growth factor beta (TGF‐β), a multifunctional cytokine, plays critical roles in immune responses. However, the precise role of TGF‐β in colitis and colitis‐associated cancer remains poorly defined. Here, it is demonstrated that TGF‐β promotes the colonic inflammation and related tumorig...

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Detalles Bibliográficos
Autores principales: Liu, Liansheng, Wang, Yalong, Yu, Shicheng, Liu, Huidong, Li, Yehua, Hua, Shan, Chen, Ye‐Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427365/
https://www.ncbi.nlm.nih.gov/pubmed/37261975
http://dx.doi.org/10.1002/advs.202300708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427365/
https://www.ncbi.nlm.nih.gov/pubmed/37261975
http://dx.doi.org/10.1002/advs.202300708

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