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Transforming Growth Factor Beta Promotes Inflammation and Tumorigenesis in Smad4‐Deficient Intestinal Epithelium in a YAP‐Dependent Manner
Transforming growth factor beta (TGF‐β), a multifunctional cytokine, plays critical roles in immune responses. However, the precise role of TGF‐β in colitis and colitis‐associated cancer remains poorly defined. Here, it is demonstrated that TGF‐β promotes the colonic inflammation and related tumorig...
Autores principales: | Liu, Liansheng, Wang, Yalong, Yu, Shicheng, Liu, Huidong, Li, Yehua, Hua, Shan, Chen, Ye‐Guang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427365/ https://www.ncbi.nlm.nih.gov/pubmed/37261975 http://dx.doi.org/10.1002/advs.202300708 |
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