Antibody‐Drug Conjugates to Treat Bacterial Biofilms via Targeting and Extracellular Drug Release

The treatment of implant‐associated bacterial infections and biofilms is an urgent medical need and a grand challenge because biofilms protect bacteria from the immune system and harbor antibiotic‐tolerant persister cells. This need is addressed herein through an engineering of antibody‐drug conjuga...

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Detalles Bibliográficos
Autores principales: Tvilum, Anne, Johansen, Mikkel I., Glud, Lærke N., Ivarsen, Diana M., Khamas, Amanda B., Carmali, Sheiliza, Mhatre, Snehit Satish, Søgaard, Ane B., Faddy, Emma, de Vor, Lisanne, Rooijakkers, Suzan H. M., Østergaard, Lars, Jørgensen, Nis P., Meyer, Rikke L., Zelikin, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427384/
https://www.ncbi.nlm.nih.gov/pubmed/37290045
http://dx.doi.org/10.1002/advs.202301340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427384/
https://www.ncbi.nlm.nih.gov/pubmed/37290045
http://dx.doi.org/10.1002/advs.202301340

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