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Antibody‐Drug Conjugates to Treat Bacterial Biofilms via Targeting and Extracellular Drug Release
The treatment of implant‐associated bacterial infections and biofilms is an urgent medical need and a grand challenge because biofilms protect bacteria from the immune system and harbor antibiotic‐tolerant persister cells. This need is addressed herein through an engineering of antibody‐drug conjuga...
Autores principales: | Tvilum, Anne, Johansen, Mikkel I., Glud, Lærke N., Ivarsen, Diana M., Khamas, Amanda B., Carmali, Sheiliza, Mhatre, Snehit Satish, Søgaard, Ane B., Faddy, Emma, de Vor, Lisanne, Rooijakkers, Suzan H. M., Østergaard, Lars, Jørgensen, Nis P., Meyer, Rikke L., Zelikin, Alexander N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427384/ https://www.ncbi.nlm.nih.gov/pubmed/37290045 http://dx.doi.org/10.1002/advs.202301340 |
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