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Sequential Ubiquitination and Phosphorylation Epigenetics Reshaping by MG132‐Loaded Fe‐MOF Disarms Treatment Resistance to Repulse Metastatic Colorectal Cancer

Abnormal epigenetic regulation is identified to correlate with cancer progression and renders tumor refractory and resistant to reactive oxygen species (ROS)‐based anti‐tumor actions. To address it, a sequential ubiquitination and phosphorylation epigenetics modulation strategy is developed and exem...

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Detalles Bibliográficos
Autores principales: Bu, Zhaoting, Yang, Jianjun, Zhang, Yan, Luo, Tao, Fang, Chao, Liang, Xiayi, Peng, Qiuxia, Wang, Duo, Lin, Ningjing, Zhang, Kun, Tang, Weizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427397/
https://www.ncbi.nlm.nih.gov/pubmed/37303273
http://dx.doi.org/10.1002/advs.202301638