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Developing Hypoimmunogenic Human iPSC‐Derived Oligodendrocyte Progenitor Cells as an Off‐The‐Shelf Cell Therapy for Myelin Disorders

Demyelinating disorders are among the most common and debilitating diseases in neurology. Canavan disease (CD) is a lethal demyelinating disease caused by mutation of the aspartoacylase (ASPA) gene, which leads to the accumulation of its substrate N‐acetyl‐l‐aspartate (NAA), and consequently demyeli...

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Detalles Bibliográficos
Autores principales: Feng, Lizhao, Chao, Jianfei, Ye, Peng, Luong, Qui, Sun, Guoqiang, Liu, Wei, Cui, Qi, Flores, Sergio, Jackson, Natasha, Shayento, Afm Nazmul Hoque, Sun, Guihua, Liu, Zhenqing, Hu, Weidong, Shi, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427412/
https://www.ncbi.nlm.nih.gov/pubmed/37271923
http://dx.doi.org/10.1002/advs.202206910