Zolbetuximab plus CAPOX in CLDN18.2-positive gastric or gastroesophageal junction adenocarcinoma: the randomized, phase 3 GLOW trial

There is an urgent need for first-line treatment options for patients with human epidermal growth factor receptor 2 (HER2)-negative, locally advanced unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma. Claudin-18 isoform 2 (CLDN18.2) is expressed in normal gastri...

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Detalles Bibliográficos
Autores principales: Shah, Manish A., Shitara, Kohei, Ajani, Jaffer A., Bang, Yung-Jue, Enzinger, Peter, Ilson, David, Lordick, Florian, Van Cutsem, Eric, Gallego Plazas, Javier, Huang, Jing, Shen, Lin, Oh, Sang Cheul, Sunpaweravong, Patrapim, Soo Hoo, Hwoei Fen, Turk, Haci Mehmet, Oh, Mok, Park, Jung Wook, Moran, Diarmuid, Bhattacharya, Pranob, Arozullah, Ahsan, Xu, Rui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427418/
https://www.ncbi.nlm.nih.gov/pubmed/37524953
http://dx.doi.org/10.1038/s41591-023-02465-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427418/
https://www.ncbi.nlm.nih.gov/pubmed/37524953
http://dx.doi.org/10.1038/s41591-023-02465-7

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