Cargando…

Rapid and stain-free quantification of viral plaque via lens-free holography and deep learning

A plaque assay—the gold-standard method for measuring the concentration of replication-competent lytic virions—requires staining and usually more than 48 h of runtime. Here we show that lens-free holographic imaging and deep learning can be combined to expedite and automate the assay. The compact im...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Tairan, Li, Yuzhu, Koydemir, Hatice Ceylan, Zhang, Yijie, Yang, Ethan, Eryilmaz, Merve, Wang, Hongda, Li, Jingxi, Bai, Bijie, Ma, Guangdong, Ozcan, Aydogan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427422/
https://www.ncbi.nlm.nih.gov/pubmed/37349390
http://dx.doi.org/10.1038/s41551-023-01057-7